Neglected Diseases


Neglected diseases are defined as diseases that disproportionately affect the world’s poorest people, including tuberculosis (TB), malaria, visceral leishmaniasis, Chagas disease, human African trypanosomiasis (HAT or sleeping sickness), and filarial worms. Despite the fact that these diseases cause significant morbidity and mortality worldwide, and that the current standards of care are difficult to administer, often have significant toxicities and are increasingly becoming less effective due to resistance, there has been little investment in developing new therapies for these diseases due to the absence of a reasonable expectation of a financial return.

Our boron chemistry platform appears to be particularly well suited for the treatment of these types of infectious diseases, and our work in this area also allows us the potential benefits of expanding the chemical diversity of our boron compounds, understanding new properties and, ultimately, if a drug is approved, potential revenue in certain jurisdictions. Until such time as we are profitable, however, we are committed to doing that research only when we can use grants and other non-dilutive sources of funding in a cash-neutral manner.